I. Key Technologies of Automatic Control of Electrical Systems in Biopharmaceutical Workshops
Programmable Logic Controllers (PLCs) play the role of the central nervous system in biopharmaceutical workshops. They can precisely control various types of equipment in the workshop, such as fermenters, filling machines, and sterilization equipment. Through pre-set program logic, PLCs can automatically adjust the operating parameters of equipment according to the real-time requirements of the production process, ensuring the stability and consistency of the production process. For example, in the fermentation process, PLCs can monitor key parameters such as temperature, pH value, and dissolved oxygen content in the fermenter in real time, and automatically control the operation of heating, stirring, aeration, and other equipment according to pre-set thresholds, maintaining the optimal fermentation environment and ensuring the stability of drug quality.
Sensors are like the "senses" of biopharmaceutical workshops, providing key data support for the automatic control system. Various types of sensors, including temperature and humidity sensors, pressure sensors, flow sensors, and biomass sensors, are widely distributed throughout the workshop to comprehensively monitor the production environment and process. In the environmental control of cleanrooms, temperature and humidity sensors provide real-time feedback on indoor temperature and humidity data. The automatic control system adjusts the operation of the air conditioning system based on this data to ensure that the cleanroom always meets the environmental requirements for drug production. The high precision and reliability of sensors are the basis for achieving the accuracy of automatic control of electrical systems.
Industrial Ethernet serves as the highway for data transmission between equipment in biopharmaceutical workshops, as well as between the control system and the management layer, ensuring the rapid and accurate transfer of information. It connects equipment such as PLCs, sensors, and host computers into an organic whole, enabling real-time data sharing and interaction. During the production process, equipment operation data can be quickly uploaded to the monitoring center through industrial Ethernet. Managers can grasp the production status in real time and issue control commands via the network, realizing remote monitoring and management. This efficient communication network significantly improves production coordination efficiency and provides strong support for the intelligent operation of the workshop.
(I) Improving Production Quality and Consistency
(II) Enhancing Production Efficiency and Capacity
(III) Reducing Energy Consumption and Operating Costs
III. Challenges and Countermeasures
Biopharmaceutical workshops involve various types of equipment and control systems, and achieving seamless integration between systems faces many challenges. The communication protocols and interface standards of different equipment suppliers may vary, increasing the difficulty of system integration. To address this challenge, at the project planning stage, unified technical standards and interface specifications need to be formulated, requiring equipment suppliers to design and manufacture equipment in accordance with the standards. At the same time, advanced system integration technologies and tools, such as middleware technology, are adopted to achieve data conversion and communication coordination between different systems, ensuring the compatibility and stability of the entire automatic control of electrical systems.
With the digital transformation of biopharmaceutical workshops, the generation and transmission of a large amount of production data pose risks to data security and privacy protection. Production data contains the core technology and trade secrets of enterprises. Once leaked, it will cause huge losses to enterprises. Therefore, a complete data security protection system needs to be established. Encryption technology is used to ensure the security of data during transmission and storage. Strict user permission management is set up to limit the access levels of different personnel to data. Network security devices such as firewalls and intrusion detection systems are deployed to prevent external illegal attacks and ensure the security and integrity of production data.
The automatic control of electrical systems in biopharmaceutical workshop engineering involves knowledge from multiple fields, such as automation, information technology, and biopharmaceutical processes, and requires a high comprehensive quality of professional talents. Currently, the shortage of such interdisciplinary professional talents in the industry restricts the promotion and application of automatic control technologies. Enterprises should strengthen cooperation with universities and scientific research institutions, carry out customized talent training programs, and provide students with practical opportunities so that they can master interdisciplinary knowledge and skills. At the same time, enterprises should strengthen employee training internally, regularly organize technical exchanges and training courses, improve the professional level of existing employees, and build a high-quality team of professional talents to provide talent support for the stable operation of automatic control of electrical systems.
Take a large biopharmaceutical enterprise as an example. Its newly built biopharmaceutical workshop introduced an advanced automatic control solution for electrical systems. By constructing a control system with PLC as the core, combined with high-precision sensors and an industrial Ethernet communication network, the full automation of the production process was achieved. In terms of production quality, the batch consistency of drugs was significantly improved, and the product qualification rate increased from the previous 90% to over 98%. Production efficiency was greatly improved, with a 50% increase in production capacity and a 30% reduction in energy consumption. When dealing with the challenges of system integration, the enterprise closely cooperated with equipment suppliers to unify technical standards and successfully achieved the integration of various systems. By establishing a complete data security protection system, the security of production data was effectively guaranteed. In addition, the enterprise actively cultivated professional talents, and the internal technical team was able to proficiently handle various problems in system operation, ensuring the efficient and stable operation of the workshop and bringing significant economic benefits and market competitiveness to the enterprise.
The automatic control of electrical systems in biopharmaceutical workshop engineering, as the core driving force for industry development, is leading profound changes in the biopharmaceutical production model. Despite facing many challenges, with the continuous advancement of technology and the joint efforts of the industry, automatic control technology will play an even more important role in the biopharmaceutical field, providing strong support for improving drug quality and protecting public health, and helping the biopharmaceutical industry move towards a more intelligent and efficient future.